Observational Research, Senior Manager (Obesity)

Company: Amgen
Location: Thousand Oaks
Posted on: January 12, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Observational Research, Senior Manager (Obesity) What you will do Lets do this. Lets change the world. Do you like to work within scientific and commercial teams to generate real-world evidence (RWE); RWE that supports an ever-changing landscape of unique and evolving business needs? If so, we invite you to explore Amgens Center for Observational Research (CfOR). Here in CfOR we are a team of scientists. We conduct observational research across the drug development and commercialization lifecycle. The data we produce informs clinical trial design, supports regulatory decision making and aids in the commercialization of our products. Study designs range from evaluating disease frequencies and current standards of care to understanding the safety and effectiveness of our medicines. We partner with internal and external teams to produce the highest quality RWE to enable rapid decision making. The goal of everything we do is to contribute to the development of the best possible medicines and bring these medicines to patients as quickly as possible. Your role as an Observational Research Senior Manager will be to lead projects and teams in support of that mission: to serve patients. You will be gathering insights and building collaborations and capabilities to advance the generation, use, and dissemination of RWE. This position will support the obesity therapeutic area and require you to be an effective communicator, critical thinker, and adept scientist. We are in an exciting time in with a constantly shifting disease landscape. Your ability to execute on the science and deliver results efficiently and effectively will be the key to your success. Responsibilities: Develop study proposals using real-world data to address key business questions as identified within the cross-functional teams. For example, identifying an appropriate database and collaborator to evaluate disease severity in a particular patient population. Lead the design, completion, and delivery of RWE. For example, build a study to evaluate the safety and effectiveness of an Amgen medicine to inform a regulatory decision (e.g., label expansion/change) and fulfill a global or regional regulatory requirement. Facilitate the dissemination of RWE through key presentations, publications and/or trainings. For example, develop a scientifically based promotional resource targeting a broad spectrum of external partners (e.g., health care providers, payers, integrated delivery networks). Collaborate on the development of an integrated evidence generation plan for the product team. This would require discussion and alignment on the conceptualization and design of real-world data studies focused on the strategies and priorities of your cross-functional partners. Contribute to the development and implementation of innovative analytic methods. For example, leverage CfORs internal data and analytics center to complete a study evaluating the comparative effectiveness of an Amgen medicine vs. an appropriate comparator. Partner with cross-functional colleagues to enhance the use of RWE. For example, develop a substitute for and/or a complement to an interventional study to reduce the time and cost of a particular drug development goal. Build external partnerships to increase the opportunities to use real-world data to support the product team. For example, identify an external partner who has access to data that can improve the quality and availability of information from different patient populations and countries. Contribute to CfORs mission in progressing innovative epidemiological methods and analytical capabilities, using real-world data, to enable rapid and informed decision making bringing better medicines to patients faster. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Senior Manager with these qualifications. Basic Qualifications: Doctorate degree and at least 2 years of related research and scientific experience OR Master's degree and at least 6 years of related research and scientific experience OR Bachelors degree and 8 years of data sciences and scientific experience OR Associates degree and 10 years of data sciences and scientific experience OR High school diploma / GED and 12 years of data sciences and scientific experience Preferred Qualifications: Doctorate degree in epidemiology or subject area with high observational research content. Experience in the ideation, design, execution and delivery of observation research studies. Excellent communication, presentation and interpersonal skills. Experience working with and leading multi-disciplinary teams. Research experience in project planning and study management. Research experience within the pharmaceutical and/or public health setting. Research experience working with secondary data systems (e.g. administrative claims, EHR, disease and/or drug registries). What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Azusa , Observational Research, Senior Manager (Obesity), Science, Research & Development , Thousand Oaks, California